Tags: Multiple Myeloma
Predicting Outcomes and Monitoring Disease in Patients With Multiple Myeloma
Abstract: Multiple myeloma (MM) is a clonal plasma cell dyscrasia and the most common form of primary bone marrow cancer. Nearly 35,000 new cases of MM […]
Novel Approaches to the Treatment of Multiple Myeloma
Abstract: The treatment landscape for multiple myeloma (MM) has evolved significantly over the last decade with the approval of novel therapies and combinations in the newly […]
Optimizing the Benefits of BCMA-Targeted CAR T-Cell Therapy in Multiple Myeloma
H&O Why is the B-cell maturation antigen (BCMA) a good target for chimeric antigen receptor (CAR) T-cell therapy in multiple myeloma? SL BCMA is an important […]
Best Practices for the Assessment of Measurable Residual Disease (MRD) in Multiple Myeloma
Abstract: Therapeutic advances in multiple myeloma have led to durable, deep remissions in a subset of patients. However, outcomes of patients achieving a complete response are not […]
Advances in the Development of Vaccines and Other Immunotherapies for Multiple Myeloma
H&O What types of immune-based therapies are in development for multiple myeloma? DA Immunotherapy is an important area in multiple myeloma, and this field encompasses […]
Delaying the Use of High-Dose Melphalan With Stem Cell Rescue in Multiple Myeloma Is Ready for Prime Time
Abstract: The significant advances made in the treatment of multiple myeloma (MM) have allowed for a paradigm shift away from the early use of high-dose […]
Hem/Onc News
Selinexor Approved for Multiple Myeloma On July 3, the US Food and Drug Administration (FDA) granted accelerated approval to selinexor (Xpovio, Karyopharm) in combination with dexamethasone […]
A Clinician’s Perspective of Treatment of Relapsed or Refractory Multiple Myeloma
Click the “Download PDF” button to read Dr. Paul G. Richardson’s perspective on treatment of relapsed or refractory multiple myeloma.
Immune-Mediated Hemolytic Anemia and Thrombocytopenia in Clonal B-Cell Disorders: A Review
Abstract: Autoimmune hemolytic anemia (AIHA) and immune thrombocytopenia purpura (ITP) have been associated with B-cell lymphoproliferative disorders. Here, we review the epidemiology, pathogenesis, diagnosis, and […]
Monitoring Multiple Myeloma
Abstract: Multiple myeloma (MM) is a B-cell malignancy characterized by the accumulation in bone marrow of terminally differentiated plasma cells. MM is a slowly growing, […]
Incorporating Monoclonal Antibodies Into the Management of Multiple Myeloma
H&O How do monoclonal antibodies work? TM Monoclonal antibodies are immunoglobulins (Igs) that are generated and manufactured to target a specific antigen present on a […]
The Effect of Novel Therapies in High-Molecular-Risk Multiple Myeloma
Abstract: Multiple myeloma is a heterogeneous disease with a prognosis that varies with patient factors, disease burden, tumor biology, and treatments. Certain molecular abnormalities confer […]
The Role of Autologous Stem Cell Transplant in Patients With Multiple Myeloma
H&O What are the clinical characteristics of multiple myeloma? JM Multiple myeloma has historically been defined by 4 clinical characteristics: elevated calcium, renal deficiency, anemia, […]
Use of Genetic Markers in Multiple Myeloma
H&O In what ways is multiple myeloma a genetically heterogeneous disease? RF In an editorial written several years ago, I referred to this disease as […]