The Seamless Approach to Drug Development in Oncology

H&O What are some drawbacks to the 3-phase approach to drug development? RP A major drawback to the conventional 3-phase program is that a stop […]

The Use of Drug Transporters as Therapeutic Targets

H&O What is the role of transporters in cell biology? KG Transporters are proteins that play a role in bringing small molecules—such as endogenous compounds, vitamins, […]

Manipulating the Microbiome to Improve the Efficacy of Immunotherapy

H&O What is known about the role of the gut microbiome in cancer? TG Research into the intersection between the commensal microbiota and cancer is just […]

FDA Regulation of Laboratory-Developed Tests

Clinical Advances in Hematology & Oncology Volume 14, Issue 5, May 2016 Vincent A. Miller, MD Chief Medical Officer Foundation Medicine Cambridge, Massachusetts H&O How are […]