Pediatric Langerhans Cell Histiocytosis: State of the Science and Future Directions

  Abstract: Langerhans cell histiocytosis (LCH) is an inflammatory neoplasm of myeloid origin characterized by the presence of classic CD1a+/CD207+ cells. An ongoing debate over the […]

Drug Development for Rare Cancers in Children

  H&O  How is a rare cancer defined? LG  Approximately 1.6 million cases of cancer are diag­nosed each year in the United States. The US Food […]

Challenges in Drug Development for Children

H&O  How common is cancer in children? PA  In the United States, there are approximately 14,500 new cases of cancer diagnosed each year in children from […]