Treatment of Acute Lymphoblastic Leukemia in Older Adults: Now and the Future

  Abstract: Acute lymphoblastic leukemia (ALL) is an uncommon disease with poor outcomes in older patients. Although intensive chemotherapy can induce complete responses in older patients, […]

BCL-2 As a Therapeutic Target in Chronic Lymphocytic Leukemia

  Abstract: Venetoclax (formerly ABT-199) was recently approved in the United States for the treatment of patients who have relapsed or refractory chronic lymphocytic leukemia (CLL) […]

The Evolution of Allogeneic Stem Cell Transplant for Children and Adolescents With Acute Myeloid Leukemia

  Abstract: Survival rates in subsets of pediatric patients who have acute myeloid leukemia (AML) with favorable risk features are now greater than 90%. However, outcomes […]

Considerations in the Frontline Treatment of Chronic Lymphocytic Leukemia

  H&O  When is frontline therapy initiated in chronic lymphocytic leukemia (CLL)? SO  The standard approach to CLL is still watch-and-wait. If patients are asymptomatic and […]

The Evolving Role of Chemoimmunotherapy in Chronic Lymphocytic Leukemia

  H&O  What has been the traditional role of chemoimmunotherapy in patients with CLL? NL Traditionally, chemoimmunotherapy was the standard approach in both the frontline and […]

The Best Frontline Therapy for CML: Imatinib?

H&O  What do we know of imatinib’s efficacy as frontline therapy in chronic myeloid leukemia (CML) patients? GS  Imatinib (Gleevec, Novartis) is the most important drug discovered in recent […]

Erythroleukemia: Clinical Course and Management

The Pure Erythroleukemia: A Case Report and Literature Review Naeem Latif, MD, Elaine Salazar, MD, Rubina Khan, MD, Bruce Villas, MD, Fauzia Rana, MD Department of Hematology/Oncology and Pathology, University of Florida […]