Archive: January 2021
Venous Thromboembolism
The Most Important Takeaways From the New ASH Guidelines for the Management of Venous Thromboembolism
Michael Blake Streiff, MD
H&O How many recent guidelines focus on the management of patients with venous thromboembolism (VTE) that is not associated with cancer? MS The guidelines we are […]
LLM
Chimeric Antigen Receptor T-Cell Therapy Targeting CD30 in Hodgkin Lymphoma
Barbara Savoldo, MD, PhD
H&O What prompted your research of chimeric antigen receptor (CAR) T-cell therapy in Hodgkin lymphoma? BS It has been known for a long time that Hodgkin […]
Oncology
Biliary Cancer: Gateway to Comprehensive Molecular Profiling
Muhammad Sardar, MD, and Rachna T. Shroff, MD, MS
Abstract: Cholangiocarcinoma is a rare malignancy with a poor prognosis. The majority of tumors present at an advanced stage, and relapse often occurs after surgery conducted […]
Breast Cancer
HER2-Positive Metastatic Breast Cancer: A Comprehensive Review
Pedro Exman, MD, and Sara M. Tolaney, MD, MPH
Abstract: Cases of human epidermal growth factor receptor 2 (HER2)–positive breast cancer represent approximately 15% to 20% of all breast cancers. Historically, this subtype of breast […]
Kidney Cancer
The Effect of Interleukin 1 Beta Blockade on the Tumor Microenvironment
Charles G. Drake, MD, PhD
Based on a presentation by Charles G. Drake, MD, PhD, at the International Kidney Cancer Symposium 2020, November 6-7, Virtual Preclinical data suggest that interleukin […]
Letter From the Editor
Letter From the Editor: One Step Closer to the End of COVID
Richard R. Furman, MD
As I sat in the chair and pushed my shirt sleeve as high as possible over my “muscular” deltoid to prepare for my first dose of […]