Refining Dosing Strategies: Lessons From Singapore’s Health Care System

H&O Could you provide an overview of the health care system in Singapore? BCG The health care system in Singapore is centered on 2 basic tenets. […]

The Development of Endoxifen for Breast Cancer

H&O Could you please describe how tamoxifen works, and its history as a treatment for breast cancer? MG Tamoxifen is a selective estrogen receptor modulator […]

Research in Drug Development for Advanced Prostate Cancer

H&O What are the standard approaches for the treatment of advanced prostate cancer? ME There are several treatments approved by the US Food and Drug […]

Drug Development for Rare Cancers in Children

H&O How is a rare cancer defined? LG Approximately 1.6 million cases of cancer are diagnosed each year in the United States. The US Food […]

Barriers to the Development of Drugs for Primary Brain Tumors

H&O What are the most common types of primary brain tumors? SC The most common types are meningioma, tumors that arise in the lining of […]

Challenges in Drug Development for Children

H&O How common is cancer in children? PA In the United States, there are approximately 14,500 new cases of cancer diagnosed each year in children from […]

The Seamless Approach to Drug Development in Oncology

H&O What are some drawbacks to the 3-phase approach to drug development? RP A major drawback to the conventional 3-phase program is that a stop […]

The I-SPY Approach to Drug Development

Clinical Advances in Hematology & Oncology October 2016, Volume 14, Issue 10 Laura Esserman, MD, MBA Professor, Departments of Surgery and Radiology Affiliate Faculty, Institute for […]