Current Issue: September 2025
Feature Article
Integration of Immunotherapy Into the Frontline Treatment of Acute Lymphoblastic Leukemia
Abstract: Immunotherapy has transformed the treatment of acute lymphoblastic leukemia (ALL) over the past 2 decades, leading to excellent outcomes in adults and children. This is […]
Advances in LLM
Is There a Universal Standard of Care for Frontline Therapy in Multiple Myeloma?
H&O What is the most common regimen for frontline treatment in multiple myeloma? SL The standard regimen in the United States for fit patients with multiple […]
Advances in Hematology
Diagnosis and Treatment of Secondary Hemophagocytic Lymphohistiocytosis in Adults
H&O What is hemophagocytic lymphohistiocytosis (HLH), and what forms of it occur? JR HLH is a hyperinflammatory response—an overactivation of the immune system that is driven […]
Advances in Drug Development
FDA Regulatory Pathways for Expedited Drug Development and Approval
H&O What are the main expedited pathways for drug approval? ASK The main expedited regulatory pathways for the development and approval of prescription drugs by the […]
CRC in Focus
The Emerging Role of Antibody-Drug Conjugates in Metastatic Colorectal Cancer
H&O How well is colorectal cancer (CRC) suited to antibody-drug conjugate (ADC) therapy, in comparison with other solid tumors? JS It has been historically challenging to […]
Supplements:
A Review of Selected Presentations From the ASCO Gastrointestinal Cancers Symposium, ASCO Annual Meeting, and ESMO Gastrointestinal Cancers Congress
This year has marked a dynamic chapter in gastrointestinal cancer research, with both practice-informing and practice-changing data emerging from key international meetings, including the American Society […]