Feature Article

Neoadjuvant Therapies in High-Risk Localized Prostate Cancer: Past, Present, and Future

Abstract: Treatment for high-risk localized prostate cancer can be particularly challenging because of an elevated risk of disease recurrence. One of the proposed ways to improve […]

Breast Cancer In Focus

The Use of Genomic Assays to Guide Chemotherapy in Breast Cancer

H&O What was the impetus for the OPTIMA trial? KK The goal of OPTIMA, which was led by investigators in the United Kingdom, was to examine […]

Advances in Hematology

Anaphylactic Reactions to Blood Transfusions: Focus on Alpha-Gal Syndrome

H&O What is alpha-gal syndrome? CG Alpha-gal syndrome is an immunoglobulin E (IgE)–mediated allergy to galactose-α-1,3-galactose, a carbohydrate found in meat from nonprimate mammals and in […]

Advances in LLM

GVHD Prophylaxis for Patients Undergoing Stem Cell Transplant

H&O What is the classic backbone regimen used after allogeneic stem cell transplant (SCT)? PK The traditional gold standard for graft-versus-host disease (GVHD) prophylaxis following allogeneic […]