Breast Cancer

Which Patients With Early-Stage Triple-Negative Breast Cancer Should Receive a Platinum?

William M. Sikov, MD

  H&O  What forms of cancer are typically treated with platinum agents? WS  Platinum analogues are used to treat a wide range of solid tumors, including […]

Melanoma

The Microbiome: A Basis for Novel Immunomodulation in Mice and Men

Hassane M. Zarour, MD

  H&O  Why does immunotherapy work better in some patients with melanoma than in others? HZ  We are still unsure about that, but we are working […]

Bladder Cancer

Immunotherapy in Urothelial Cancer, Part 2: Adjuvant, Neoadjuvant, and Adjunctive Treatment

Steven S. Yu, MD, Leslie K. Ballas, MD, Eila C. Skinner, MD, Tanya B. Dorff, MD, Sarmad Sadeghi, MD, PhD, and David I. Quinn, MBBS (Hons), PhD, FRACP, FACP

  Abstract:  Urothelial cancer, which is predominantly seen in men, is common throughout the world. Most disease presents as non–muscle invasive bladder cancer (NMIBC), with cancer […]

Leukemia

Philadelphia Chromosome–Like Acute Lymphoblastic Leukemia: Progress in a New Cancer Subtype

Julia Wells, PhD, Nitin Jain, MD, and Marina Konopleva, MD, PhD

  Abstract: Philadelphia chromosome–like (Ph-like) acute lymphoblastic leukemia (ALL) is a newly described, high-risk subtype of B-cell ALL. It is characterized by a gene expression profile […]

Hematology

New Insights Into Cytomegalovirus Infection After Allogeneic Hematopoietic Stem Cell Transplant

Michael Boeckh, MD, PhD

  H&O  How common is CMV infection among patients undergoing allogeneic hematopoietic stem cell transplant? MB Cytomegalovirus (CMV) reactivation occurs in approximately 50% to 70% of […]

Leukemia

Identifying Patients With Leukemia Who Are at Risk for Fungal Infections

Vijaya Raj Bhatt, MD

  H&O  Approximately how many patients with leukemia will develop fungal infections? VB  The risk of fungal infection varies according to several factors, such as the […]

Kidney Cancer

Highlights in Kidney Cancer

Highlights in Kidney Cancer: From the American Society of Clinical Oncology Genitourinary Cancers Symposium February 16-18, 2017 • Orlando, Florida Computer Assistance Reduces Errors in Evaluation […]

Hem/Onc News

Hem/Onc News

Devon Schuyler

Recombinant Factor IX Approved for Use in Adults and Children With Hemophilia B The US Food and Drug Administration (FDA) approved the recombinant coagulation factor IX […]

Letter From the Editor

ASCO Cage Match: BR vs R-CHOP

Brad S. Kahl, MD

I recently attended the ASCO annual meeting in Chicago. It’s huge, but remarkably organized and well run. I think it helps that the meeting has been held […]