Archive: August 2022
Feature Article
Hematologic Concerns in Transgender Patients
Abstract: Patients with gender dysphoria are increasingly seeking gender-affirming therapies, which can have adverse hematologic effects. For example, estrogen can increase the risk for arterial and […]
Feature Article
New Treatment Strategies for Waldenström Macroglobulinemia
Abstract: The development of high-throughput technologies has allowed us to characterize the molecular landscape of hematologic neoplasms and identify somatic mutations. As a result, we can […]
Advances in LLM
The Future Role of Bispecific Antibodies in Lymphoma
H&O What is the mechanism of action of bispecific antibodies? JA Bispecific antibodies aim to harness the power of the immune system. These treatments are monoclonal […]
CRC in Focus
The Emerging Role of KRAS G12C Inhibitors in the Treatment of Locally Advanced or Metastatic Colorectal Cancer
H&O How common are KRAS G12C mutations in locally advanced or metastatic colorectal cancer? KC RAS mutations overall are quite common in colorectal cancer (CRC) and […]
Letter From the Editor
I Think the FDA Got It Wrong …
We have experienced a string of great successes in clinical therapeutics for CLL over the past several years, both in the number of novel therapies approved […]
CLL
Clinical Use of Measurable Residual Disease in CLL
H&O What are some of the limitations of the International Workshop on CLL (iwCLL) response criteria for chronic lymphocytic leukemia (CLL) in the era of novel […]
Prostate Cancer In Focus
When to Use Somatic Tumor Testing in Prostate Cancer
H&O Which patients with prostate cancer are eligible for somatic tumor testing? TF To begin with, we should be clear about some definitions. Somatic tumor testing […]