Refining the Standard of Care in Immune Thrombotic Thrombocytopenic Purpura

Abstract: Acute immune thrombotic thrombocytopenic purpura (iTTP) is a medical emergency. In the setting of any thrombotic microangiopathy (TMA), blood should be drawn to measure ADAMTS13 […]

Management Options for Node-Positive Muscle-Invasive Bladder Cancer

Abstract: Localized node-positive bladder cancer is characterized by a high degree of heterogeneity, leading to significant variability in overall survival outcomes among affected individuals. The absence […]

Management of Oligometastatic Hormone-Sensitive Prostate Cancer

H&O  How is oligometastatic defined in the context of hormone-sensitive prostate cancer (HSPC)? PT  We used to make a binary distinction between localized HSPC, which is […]

Is Luspatercept the New Standard of Care in Transfusion-Dependent Low-Risk Myelodysplastic Syndromes?

H&O  What is luspatercept, and how does it work for patients who have anemia associated with transfusion-dependent low-risk myelodysplastic syndromes (LR-MDS)? GCM  Luspatercept (Reblozyl, Celgene/BMS) is […]

Letter From the Editor: Incentive Planning

Entering the field of oncology means caring for patients who may die of their disease, and it takes a certain type of person to do this […]

Doublet vs Triplet Combinations for Frontline Treatment of Chronic Lymphocytic Leukemia

H&O  What are the advantages of doublet combinations over single-agent Bruton tyrosine kinase (BTK) inhibitor therapy in the frontline therapy of chronic lymphocytic leukemia (CLL)? NJ  […]

The Emerging Role of Immunotherapy-Based Strategies in Nonmetastatic Colorectal Cancer

H&O  What makes immunotherapy an appealing option for patients with nonmetastatic colorectal cancer (CRC)? MC  Immunotherapy has become important because it is more effective than chemotherapy […]

The Global Cardio-Oncology Registry

H&O  How did the field of cardio-oncology come about? DS  There are about 20 million cancer survivors in the United States. With significant improvements in immunotherapy, […]

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