Feature Article

Integration of Immunotherapy Into the Frontline Treatment of Acute Lymphoblastic Leukemia

Abstract: Immunotherapy has transformed the treatment of acute lymphoblastic leukemia (ALL) over the past 2 decades, leading to excellent outcomes in adults and children. This is […]

Advances in LLM

Is There a Universal Standard of Care for Frontline Therapy in Multiple Myeloma?

H&O What is the most common regimen for frontline treatment in multiple myeloma? SL The standard regimen in the United States for fit patients with multiple […]

Advances in Hematology

Diagnosis and Treatment of Secondary Hemophagocytic Lymphohistiocytosis in Adults

H&O What is hemophagocytic lymphohistiocytosis (HLH), and what forms of it occur? JR HLH is a hyperinflammatory response—an overactivation of the immune system that is driven […]

Advances in Drug Development

FDA Regulatory Pathways for Expedited Drug Development and Approval

H&O What are the main expedited pathways for drug approval? ASK The main expedited regulatory pathways for the development and approval of prescription drugs by the […]

CRC in Focus

The Emerging Role of Antibody-Drug Conjugates in Metastatic Colorectal Cancer

H&O How well is colorectal cancer (CRC) suited to antibody-drug conjugate (ADC) therapy, in comparison with other solid tumors? JS It has been historically challenging to […]