Feature Article

Precision Medicine in Advanced Hormone Receptor–Positive Breast Cancer: Integrating Genomic Profiling and Liquid Biopsy Into Clinical Practice

Abstract: Precision medicine has reshaped the management of advanced hormone receptor–positive, human epidermal growth factor receptor 2–negative breast cancer by coupling treatment with tumor genomics rather […]

Letter From the Editor

Letter From the Editor: The Waiting Game

If you have ever had to wait for health care—whether an appointment, a test, or the result of a test—the anticipation of the possible outcomes and […]

Prostate Cancer In Focus

The Clinical Implications of the PROTEUS Trial

H&O What was the impetus for the PROTEUS trial?1 MET The standard treatment for many patients with solid tumors is a combination of surgery to remove […]

CLL in Focus

Optimizing CLL Treatment After Covalent BTK Inhibition

H&O What is the standard covalent Bruton tyrosine kinase (BTK) inhibitor regimen for chronic lymphocytic leukemia (CLL)? CC I typically use covalent BTK inhibitors as monotherapy, […]