Archive: August 2016
Letter From the Editor
Letter From the Editor: From 2003 to Today
Clinical Advances in Hematology & Oncology Volume 14, Issue 9, September 2016 It is mid-August. The air is stifling, dripping, melting—making it almost, but not […]
Kidney Cancer
Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma
Lisly J. Chery, MD, Jose A. Karam, MD, and Christopher G. Wood, MD
Abstract: The incidence of renal cell carcinoma is increasing, with up to one-third of patients presenting with metastatic disease. Combination therapy is used to prolong […]
Feature Article
The Role of High-Dose Melphalan and Autologous Stem Cell Transplant in the Rapidly Evolving Era of Modern Multiple Myeloma Therapy
Clinical Advances in Hematology & Oncology Volume 14, Issue 9, September 2016 Peter M. Voorhees, MD, and Saad Z. Usmani, MD The authors are affiliated with […]
Hematology
Zika and the Safety of the US Blood Supply
Michael P. Busch, MD, PhD
H&O What exactly is the Zika virus, and when was it discovered? MB The Zika virus was discovered in 1947 in the Zika Forest of […]
Breast Cancer
Management of Brain Metastases in Breast Cancer
Carey K. Anders, MD
H&O How common are brain metastases? CA Lung cancer, melanoma, and breast cancer are the 3 types of cancers that are most likely to metastasize […]
Advances in LLM
Consolidation Therapy After Autologous Stem Cell Transplant in Relapsed/Refractory Hodgkin Lymphoma
Clinical Advances in Hematology & Oncology Volume 14, Issue 9, September 2016 Craig H. Moskowitz, MD Steven A. Greenberg Chair in Lymphoma Research Clinical Director, Division […]
Prostate Cancer In Focus
Special Concerns for Survivors of Prostate Cancer
Clinical Advances in Hematology & Oncology Volume 14, Issue 9, September 2016 Andrew C. Peterson, MD Professor of Urologic Surgery Duke University School of Medicine Durham, […]
Advances in Drug Development
The Importance of Dose Optimization Prior to Initiation of a Registration Trial
Clinical Advances in Hematology & Oncology Volume 14, Issue 9, September 2016 Nam Atiqur Rahman, PhD Director Division of Clinical Pharmacology V Center for Drug Evaluation […]
Erratum
An article in the July 2016 issue, “Bruton’s tyrosine kinase inhibitors in chronic lymphocytic leukemia and lymphoma” by Gaurav Varma, MSPH, Tyler P. Johnson, MD, and […]
Letter From the Editor
Letter from the Editor: The Campaign Button
Clinical Advances in Hematology & Oncology Volume 14, Issue 8, August 2016 In early June, after the US presidential contest had essentially been narrowed down […]
Colorectal Cancer
Trifluridine/Tipiracil and Regorafenib: New Weapons in the War Against Metastatic Colorectal Cancer
Benjamin A. Weinberg, MD, John L. Marshall, MD, and Mohamed E. Salem, MD
Abstract: Colorectal cancer (CRC) is the second leading cause of cancer-related death in the United States. Approximately 20% of patients have metastatic disease at diagnosis, […]
Ovarian Cancer
The Status of Poly(Adenosine Diphosphate-Ribose) Polymerase (PARP) Inhibitors in Ovarian Cancer, Part 1: Olaparib
Rowan E. Miller, MD, and Jonathan A. Ledermann, MD
Abstract: Poly(adenosine diphosphate-ribose) polymerase (PARP) inhibitors have shown promising clinical activity in epithelial ovarian cancer. Following the observation in vitro that PARP inhibition is synthetically […]
Lung Cancer in Focus
Moving Beyond Monotherapy in the Immunotherapeutic Arena: Prospects for Combination Therapies in Lung Cancer
Clinical Advances in Hematology & Oncology Volume 14, Issue 8, August 2016 Lung Cancer in Focus Scott J. Antonia, MD, PhD Chair of the Thoracic […]
Advances in LLM
Are We Ready for Precision Medicine in Acute Myeloid Leukemia?
Clinical Advances in Hematology & Oncology Volume 14, Issue 8, August 2016 Advances in LLM Gail J. Roboz, MD Professor of Medicine Weill Cornell Medicine […]
Kidney Cancer in Focus
Highlights in Kidney Cancer From the 2016 American Society of Clinical Oncology Annual Meeting
Clinical Advances in Hematology & Oncology Volume 14, Issue 8, August 2016 Highlights in Kidney Cancer From the 2016 American Society of Clinical Oncology Annual Meeting […]
Melanoma in Focus
The Role of Talimogene Laherparepvec (T-VEC) in the Age of Checkpoint Inhibitors
Clinical Advances in Hematology & Oncology Volume 14, Issue 8, August 2016 Robert H. Andtbacka, MD, CM Associate Professor of Surgery University of Utah Huntsman Cancer […]
Clinical Update
Recent Advances in the Management of Myelofibrosis
Clinical Advances in Hematology & Oncology Volume 14, Issue 8, August 2016 Ruben A. Mesa, MD Consultant Hematologist Chair, Division of Hematology & Medical Oncology Deputy […]
HCC In Focus
Sorafenib in Combination With Transarterial Chemoembolization for the Treatment of Hepatocellular Carcinoma
Clinical Advances in Hematology & Oncology Volume 14, Issue 8, August 2016 Jean-Francois H. Geschwind, MD Chairman, Department of Radiology and Biomedical Imaging Professor of Radiology […]
Advances in Drug Development
Improving Clinical Trial Design Through Quantitative Pharmacology
Clinical Advances in Hematology & Oncology Volume 14, Issue 8, August 2016 Michael L. Maitland, MD, PhD Director of Therapeutics Inova Center for Personalized Health […]