Breast Cancer

Energy Balance in Advanced Breast Cancer: Extending Beyond the Curative Setting

Abstract: Outcomes in early-stage breast cancer, including quality of life, body composition, physical functioning, physiologic biomarkers, cancer recurrence, and mortality, are associated with body weight, diet, […]

Breast Cancer In Focus

Lessons From Recent Trials of Antibody-Drug Conjugates in Breast Cancer

H&O Could you describe the activity and safety results of the DESTINY-Breast04 trial? PT DESTINY-Breast04 was a landmark phase 3 trial that compared trastuzumab deruxtecan, also […]

CLL

The Use of Zanubrutinib in Chronic Lymphocytic Leukemia

H&O What makes the various Bruton tyrosine kinase (BTK) inhibitors different from one another? DB A variety of BTK inhibitors have been approved for use in […]

CRC in Focus

The Use of Immunotherapy in Metastatic Microsatellite-Stable Colorectal Cancer

H&O What percentage of cases of metastatic colorectal cancer (CRC) fall into the microsatellite-stable (MSS) category? CL Approximately 95% to 96% of patients with metastatic CRC […]

HCC In Focus

The Evolving Role of Combination Systemic Therapies in Hepatocellular Carcinoma

H&O What are the treatment goals in hepatocellular carcinoma? RK In hepatocellular carcinoma (HCC), the treatment goals depend on the stage of the cancer. For early-stage […]

Letter From the Editor

Letter From the Editor: The Third Tier

I recently completed another two-week rotation on the lymphoma service at NewYork-Presbyterian Hospital/Weill Cornell Medicine, which always provides me with much food for thought. Many topics of […]

Advances in LLM

Targeting the Microbiome to Improve Outcomes in Stem Cell Transplant

H&O What are the characteristics of a healthy microbiome? DP A healthy microbiome is dynamic and diverse. It consists of many different types of commensal bacteria—predominantly […]