Letter From the Editor
Letter From the Editor: Addressing the Racial Gap in Health Care
Case Study Series
Case Study Series: Improving Outcomes in Pediatric NTRK Gene Fusion-Positive Solid Tumors: Importance of Genomic Testing and Targeted Therapy With the TRK Inhibitor Larotrectinib
In the Clinic: Case Studies Let us begin our discussion with 2 pediatric cases that prompt the question, “How will you proceed?” Patient 1: A baby […]
In This Issue
From Recent Issues
Feature Article
Immune Checkpoint Inhibitor Therapy in Locally Advanced MSI GI Malignancies
Abstract: Locally advanced gastrointestinal (GI) malignancies have conventionally been treated in a multimodal fashion that combines (neo)adjuvant chemotherapy with or without radiation and definitive surgical resection. […]
Feature Article
Increasing Inclusion and Equity for Black Women in Breast Cancer Clinical Trials
Abstract: Black women diagnosed with breast cancer experience a disproportionately high mortality rate. The disparity in outcomes between Black and White women is multifactorial, with a […]
Feature Article
The Role of Noncovalent BTK Inhibitors in the Era of Covalent BTK Inhibitors
Abstract: Despite significantly improving outcomes in patients with B-cell malignancies, covalent Bruton tyrosine kinase (BTK) inhibitors are limited by toxicities and the development of resistance. Some […]
Supplements
Highlights in Metastatic Urothelial Cancer From the European Society for Medical Oncology Congress 2023
A Review of Selected Presentations From the ESMO Congress 2023 • October 20-24, 2023 • Madrid, Spain The Double Antibody Drug Conjugate (DAD) Phase I […]
breast cancer
Highlights in Metastatic Breast Cancer from the 2022 San Antonio Breast Cancer Symposium
A Review of Selected Presentations from SABCS 2022 • San Antonio, TX • December 6-10, 2022 EMERALD Phase 3 Trial of Elacestrant Versus Standard of Care […]
triple-negative breast cancer
Year-End Highlights in Metastatic Triple-Negative Breast Cancer from the 2022 American Society of Clinical Oncology Annual Meeting, and the European Society for Medical Oncology Congress and Breast Cancer Congress
A Review of Selected Presentations from ASCO 2022, Chicago, IL, June 3-7, 2022; ESMO Breast Cancer Congress 2022, Berlin, Germany, May 3-5 2022; and ESMO Congress […]
Kidney Cancer
Contemporary Management of Advanced Renal Cell Carcinoma
Abstract: Kidney cancer is the eighth most commonly diagnosed cancer in the United States, and nearly one-third of patients have locally advanced or metastatic disease […]
How We Treat Brain Metastases in Metastatic Renal Cell Carcinoma
Overview • Brain metastasis in patients with metastatic renal cell carcinoma generally signifies a poor prognosis. • Surgical resection is an option for patients with […]
Non–Clear Cell Renal Cell Carcinomas: Biological Insights and Therapeutic Challenges and Opportunities
Abstract: The non–clear cell renal cell carcinomas (nccRCCs) are a diverse group of rare-variant renal carcinomas. Each subtype harbors a distinct cell of origin and […]