Archive: May 2016

HSP90 Inhibitors in Lung Cancer: Promise Still Unfulfilled

Suman Chatterjee, PhD, Saveri Bhattacharya, DO, Mark A. Socinski, MD, and Timothy F. Burns, MD, PhD

Abstract: Despite recent advances in the treatment of lung cancer, non–small cell lung cancer (NSCLC) remains the leading cause of cancer-related deaths in the United States […]

FDA Regulation of Laboratory-Developed Tests

Clinical Advances in Hematology & Oncology Volume 14, Issue 5, May 2016 Vincent A. Miller, MD Chief Medical Officer Foundation Medicine Cambridge, Massachusetts H&O How are […]

Prevention and Treatment of Stroke in Patients With Sickle Cell Disease

Adetola A. Kassim, MD

H&O What types of stroke occur in people with sickle cell anemia (SCA)? AK Overt strokes occur in approximately 5% to 10% of children with sickle […]

Current Understanding of Resistance to Abiraterone and Enzalutamide in Advanced Prostate Cancer

Emmanuel S. Antonarakis, MD

H&O How common is resistance to abiraterone and enzalutamide in castration-resistant prostate cancer (CRPC)? ESA Approximately 15% to 25% of patients with CRPC do not respond to […]

Preventive Strategies for Invasive Aspergillus in Acute Myelogenous Leukemia

Clinical Advances in Hematology & Oncology Volume 14, Issue 5, May 2016 Gary Schiller, MD Professor of Medicine Division of Hematology/Oncology David Geffen School of Medicine […]

What Should Standard Frontline Therapy Be in Older Patients With Chronic Lymphocytic Leukemia?

Clinical Advances in Hematology & Oncology Volume 14, Issue 5, May 2016 Jennifer A. Woyach, MD, vs Clemens-Martin Wendtner, MD Now that ibrutinib (Imbruvica, Pharmacyclics/Janssen), a […]

Angiogenesis Inhibition for the Treatment of Non–Small Cell Lung Cancer

Clinical Advances in Hematology & Oncology Volume 14, Issue 5, May 2016 Mark A. Socinski, MD Professor of Medicine and Cardiothoracic Surgery University of Pittsburgh Medical Center […]

Hem/Onc News

Clinical Advances in Hematology & Oncology Volume 14, Issue 5, May 2016 Devon Schuyler Venetoclax Approved for Use in Chronic Lymphocytic Leukemia The US Food and […]

Letter From the Editor: The Pedant and the Scoundrel

Clinical Advances in Hematology & Oncology Volume 14, Issue 5, May 2016 Bruce D. Cheson, MD I usually enjoy expanding my vocabulary. Indeed, the Wordsmith website […]

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