Archive: January 2017
Colorectal Cancer
Right-Sided vs Left-Sided Colorectal Cancer
Alan P. Venook, MD
H&O What is the definition of right-sided vs left-sided colon cancer? AV In the analysis of the Cancer and Leukemia Group B (CALGB)/SWOG 80405 trial […]
Leukemia
The Evolution of Allogeneic Stem Cell Transplant for Children and Adolescents With Acute Myeloid Leukemia
Allyson Flower, MD, and Mitchell S. Cairo, MD
Abstract: Survival rates in subsets of pediatric patients who have acute myeloid leukemia (AML) with favorable risk features are now greater than 90%. However, outcomes […]
Prostate Cancer
Circulating Tumor Cells in Prostate Cancer: Beyond Enumeration
Jie-Fu Chen, MD, Yi-Tsung Lu, MD, Shirley Cheng, BS, Hsian-Rong Tseng, PhD, Robert A. Figlin, MD, and Edwin M. Posadas, MD
Abstract: Circulating tumor cells (CTCs) are a population of rare cancer cells that have detached from the primary tumor and/or metastatic lesions and entered the […]
Gastrointestinal Cancer
Molecular Biology of Gastroesophageal Cancers: Opportunities and Challenges
Shaheer Khan, DO, Sameh Mikhail, MBBCh, Joanne Xiu, PhD, and Mohamed E. Salem, MD
Abstract: Gastroesophageal (GE) malignancies make up a significant and growing segment of newly diagnosed cancers. Approximately 80% of patients who have GE cancers die within […]
Hematology
Superficial Vein Thrombosis: New Perspectives and Observations From Recent Clinical Trials
Benilde Cosmi, MD, PhD
H&O What is superficial vein thrombosis, and how common is it? BC Superficial vein thrombosis (SVT) is the preferred term to indicate thrombosis of any […]
Prostate Cancer
Prognostic Biomarkers in Early-Stage Prostate Cancer
Eric Klein, MD
H&O What is the traditional way for oncologists to determine prognosis in early-stage prostate cancer? EK The tools traditionally used to determine prognosis are the […]
Lymphoma
Aggressive B-Cell Lymphoma: The Double-Hit and Double-Expressor Phenotypes
Sonali M. Smith, MD
H&O What are some recent developments in the understanding of genetics in aggressive B-cell lymphoma? SS There are between 60 and 80 different types of […]
Pediatric Cancer
Challenges in Drug Development for Children
Peter C. Adamson, MD
H&O How common is cancer in children? PA In the United States, there are approximately 14,500 new cases of cancer diagnosed each year in children from […]
Letter From the Editor
Letter From the Editor: The ASH Rehash
Brad S. Kahl, MD
As I sit down to compose my first Letter From the Editor, I must admit to a certain amount of insecurity. For the past 14 years, […]