Right-Sided vs Left-Sided Colorectal Cancer

Alan P. Venook, MD

  H&O  What is the definition of right-sided vs left-sided colon cancer? AV  In the analysis of the Cancer and Leukemia Group B (CALGB)/SWOG 80405 trial […]

The Evolution of Allogeneic Stem Cell Transplant for Children and Adolescents With Acute Myeloid Leukemia

Allyson Flower, MD, and Mitchell S. Cairo, MD

  Abstract: Survival rates in subsets of pediatric patients who have acute myeloid leukemia (AML) with favorable risk features are now greater than 90%. However, outcomes […]

Circulating Tumor Cells in Prostate Cancer: Beyond Enumeration

Jie-Fu Chen, MD, Yi-Tsung Lu, MD, Shirley Cheng, BS, Hsian-Rong Tseng, PhD, Robert A. Figlin, MD, and Edwin M. Posadas, MD

  Abstract: Circulating tumor cells (CTCs) are a population of rare cancer cells that have detached from the primary tumor and/or metastatic lesions and entered the […]

Molecular Biology of Gastroesophageal Cancers: Opportunities and Challenges

Shaheer Khan, DO, Sameh Mikhail, MBBCh, Joanne Xiu, PhD, and Mohamed E. Salem, MD

  Abstract:  Gastroesophageal (GE) malignancies make up a significant and growing segment of newly diagnosed cancers. Approximately 80% of patients who have GE cancers die within […]

Superficial Vein Thrombosis: New Perspectives and Observations From Recent Clinical Trials

Benilde Cosmi, MD, PhD

  H&O  What is superficial vein thrombosis, and how common is it? BC  Superficial vein thrombosis (SVT) is the preferred term to indicate thrombosis of any […]

Prognostic Biomarkers in Early-Stage Prostate Cancer

Eric Klein, MD

  H&O  What is the traditional way for oncologists to determine prognosis in early-stage prostate cancer? EK  The tools traditionally used to determine prognosis are the […]

Aggressive B-Cell Lymphoma: The Double-Hit and Double-Expressor Phenotypes

Sonali M. Smith, MD

  H&O  What are some recent developments in the understanding of genetics in aggressive B-cell lymphoma? SS  There are between 60 and 80 different types of […]

Challenges in Drug Development for Children

Peter C. Adamson, MD

H&O  How common is cancer in children? PA  In the United States, there are approximately 14,500 new cases of cancer diagnosed each year in children from […]

Letter From the Editor: The ASH Rehash

Brad S. Kahl, MD

As I sit down to compose my first Letter From the Editor, I must admit to a certain amount of insecurity. For the past 14 years, […]

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