Archive: May 2022

CAR T-Cell Therapy for Relapsed/Refractory Non-Hodgkin’s Lymphoma: A Comprehensive Review

Abstract: Non-Hodgkin lymphoma (NHL) is the seventh most common type of malignancy worldwide, with approximately 544,000 cases diagnosed in 2020.1-3 The vast majority of NHLs are […]

Systemic Management of Brain Metastases in HER2+ Breast Cancer in 2022

Abstract: Up to half of all patients with metastatic human epidermal growth factor receptor 2–positive (HER2+) breast cancer will eventually acquire brain metastases (BrMs), which are […]

Radiation Therapy and Immunotherapy in Locally Advanced NSCLC

H&O  What is standard treatment in locally advanced non–small cell lung cancer (NSCLC)? PL  Standard treatment in locally advanced NSCLC used to be 6 weeks of […]

Who Is a Candidate for Nonoperative Management of Early-Stage Rectal Cancer?

H&O  What is standard treatment for early-stage rectal cancer?  CH  Surgery is the standard treatment for early-stage rectal cancer. In patients with T1N0 disease, the standard […]

New Approaches to T-Cell Acute Lymphoblastic Leukemia

H&O How common is T-cell acute lymphoblastic leukemia (T-ALL)? DT  ALL is uncommon, accounting for approximately 6700 new diagnoses per year in the United States. Between […]

Emerging Targets in Kidney Cancer: Opportunities for Drug Development

H&O  How common is kidney cancer? WS  Kidney cancer, also known as renal cancer, is an unusual—although perhaps not rare—cancer. There are approximately 76,000 new cases […]

Update on Metastatic Hormone-Sensitive Prostate Cancer

H&O  How often do men present with de novo metastatic prostate cancer?  KC  In places where we do a lot of screening, such as the United […]

How Early Intervention Impacts Long-Term Survival in Myelofibrosis

H&O  What are the signs and symptoms indicating that a patient with myelofibrosis requires treatment?  SV  According to standard practice, there are typically 3 indications for […]

Letter From the Editor: Back Together: Rebuilding Our Professional Culture

If you are like me, the weight of the pandemic has become so chronic that you have forgotten what the old way of life felt like. […]

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